Researchers have identified that body odors, particularly those emanating from the armpits, are generated by bacteria that metabolize sweat produced by the apocrine glands.
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These naturally occurring skin bacteria vary from one individual to another, which explains the observed differences in odors. While deodorants are commonly used to mask these odors, a team of researchers from the Osaka Metropolitan University is exploring an innovative way to eliminate these odor-causing bacteria.
In a study published in the Journal of Investigative Dermatology, these researchers collected body fluid samples from the armpits of 20 healthy men. The participants were divided into two groups based on the intensity of their body odor, with 11 of them exhibiting a more pronounced odor. Analysis revealed an increase in the precursors responsible for odors and a proliferation of Staphylococcus hominis bacteria in those with a more pronounced odor.
The research team, led by Professor Satoshi Uematsu and Associate Professor Kosuke Fujimoto of the Osaka Metropolitan University, then studied a bacteriophage, a virus that specifically targets bacteria, capable of infecting S. hominis. They synthesized a lysin from this bacteriophage and found, in in vitro experiments, that this lysin targeted only S. hominis without affecting other bacteria normally present on the skin.
Dr. Miki Watanabe, of the Osaka Metropolitan University, notes that armpit odors are one of the few dermatological disorders where bacteria are the main cause. While many patients suffer from this issue, there are currently few effective therapeutic options available. This discovery paves the way for new therapies to treat this recurring problem.