Cannabis reduces blood vessel function by half

Cannabis consumption, whether smoked or in edible form, is harmful to the heart and blood vessels. A recent study reveals concerning effects on blood circulation.

Researchers at UCSF found that people who regularly consume cannabis have nearly a 50% reduction in vascular function. This decline could promote conditions like hypertension and heart attacks.


To reach these conclusions, researchers studied 55 healthy adults who consume cannabis at least three times a week. None of them smoked nicotine. They compared the effects between smokers and edible consumers.

Regular smokers, averaging ten years of use, also showed changes in their blood that are harmful to blood vessel walls. These issues were not visible in edible consumers, suggesting that smoking releases additional harmful substances.

It therefore appears that the method of cannabis consumption impacts vascular health. Although THC is present in both forms, smokers experience additional effects due to combustion.

How does THC affect blood vessels?

THC, the main active compound in cannabis, acts on a system present throughout the body, including blood vessels. It can disrupt their ability to contract and dilate, which is essential for proper circulation.

This compound may also promote inflammation of blood vessel walls, reducing their flexibility and thus their proper function. It could also interfere with the production of nitric oxide, a molecule important for regulating blood pressure.

Public health implications

With the increasing legalization of cannabis, understanding its effects has become essential. This study shows that it is important to inform consumers about the risks to the heart and blood vessels, particularly depending on the method of consumption.

Health authorities could use this data to better prevent risks. Healthcare professionals should also be trained to raise awareness among patients, especially those who already have cardiovascular risk factors.