This thistle compound accelerates nerve regeneration

A new hope for nerve regeneration has been uncovered thanks to a study conducted by researchers at the University of Cologne. These scientists have discovered an innovative use for cnicin, a substance found in blessed thistle.


Individuals with nerve injuries often face a long and difficult recovery path due to the extended lengths required for axon (nerve fibers) regeneration. This study showed that cnicin can significantly accelerate axon growth, thereby providing valuable assistance to patients. The results demonstrate that this substance promotes quick nerve regeneration, preventing irreversible functional deficits.

The researchers used both animal models and human cells to study the effects of cnicin. Daily administration of this compound in mice and rats quickly improved paralysis and neuropathy. Moreover, cnicin offers a crucial advantage over other similar compounds: it can be orally ingested, thus eliminating the need for intravenous injections.

However, it is critical to determine the precise dosage of cnicin, as its efficacy depends on a specific therapeutic window. Doses that are too low or too high may be ineffective. Therefore, additional clinical studies on humans are pivotal to fully assess its therapeutic potential.

This study, partly funded by the Federal Ministry of Education and Research within the framework of the PARREGERON project, paves the way for further research and development in the field of nerve regeneration.