🔥 Making your body think it's cold: a method for easy weight loss?

Published by Adrien,
Source: eLife
Other Languages: FR, DE, ES, PT

The idea of losing weight without effort often seems too good to be true, yet our body has natural mechanisms that could help us. While traditional diets require iron discipline, researchers are exploring more subtle ways to activate our metabolism.

The team from the University of Southern Denmark focused their work on two specific amino acids present in our daily diet. Methionine and cysteine, abundant in animal proteins, were found to play a surprising role in regulating our energy expenditure. Scientists observed that reducing their consumption triggered a metabolic response similar to that caused by cold.


For seven days, researchers modified the diet of laboratory mice by limiting these two particular amino acids. The animals subjected to this special diet showed a 20% increase in their thermogenesis, without changing their physical activity or food consumption. They simply produced more body heat, leading to significant weight loss.

This increased energy burn occurred mainly in what's called beige adipose tissue, a particular form of fat present under the skin. This type of fat has the remarkable ability to burn calories to generate heat, whether the stimulus comes from cold or dietary changes. The mechanism appears identical in both cases.

The potential implications of this discovery are multiple. Researchers are already considering practical applications, such as developing functional foods low in these specific amino acids. They're also questioning the possibility of combining this nutritional approach with existing obesity treatments.

The study published in eLife opens interesting perspectives, although researchers remain cautious about immediate application in humans. Vegetarian and vegan diets, naturally low in methionine and cysteine, could explain some health benefits observed among their followers, but additional studies are needed to confirm this hypothesis.

Thermogenesis: how our body produces heat


Thermogenesis represents all the processes by which our body generates heat. This natural phenomenon allows us to maintain a constant body temperature, essential for the proper functioning of our organs. When we're exposed to cold, our body automatically activates these mechanisms to warm us up, which explains why we shiver when the temperature drops.

Our basal metabolism already consumes energy to ensure our vital functions, but thermogenesis adds an additional expenditure. It can be triggered by different factors like cold exposure, food digestion, or physical activity. Each of these stimuli activates specific metabolic pathways that result in heat production.

Brown and beige adipose tissue play a central role in this process. Unlike white fat that stores energy, these specialized fats have the unique ability to burn lipids to generate heat. They contain particular mitochondria that function like real thermal power plants at the microscopic level.

Understanding the mechanisms of thermogenesis opens interesting therapeutic perspectives. By mastering these natural processes, it could become possible to help the body burn more calories without conscious effort. This approach would represent an interesting alternative to traditional restrictive diets.
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