Mini-strokes may cause persistent fatigue �

Mini-strokes may leave persistent fatigue in more than half of patients, revealing an often overlooked burden after initial recovery. This fatigue can last up to a year, particularly in those with a history of anxiety or depression.

A transient ischemic attack (TIA), commonly called a mini-stroke, is generally considered a temporary interruption of blood flow to the brain. Symptoms, such as speech difficulties or muscle weakness, usually disappear within 24 hours. However, a recent study published in Neurology shows that the consequences may be more lasting than expected.


Researchers followed 354 people, with an average age of 70, who had experienced a mini-stroke. They assessed their fatigue levels multiple times over a year. The results indicate that 61% of participants felt fatigued two weeks after the event, and 54% continued to suffer from it up to a year later.

The study also explored five different types of fatigue, ranging from physical to mental fatigue. Average fatigue scores slightly decreased over time but remained significant. Interestingly, brain scans did not explain this persistent fatigue.

A history of anxiety or depression was identified as a major risk factor for long-term fatigue. The authors emphasize the importance of extended follow-up to identify patients who may require additional care.

One limitation of the study is that some questionnaires may have been completed with the help of relatives, which could influence responses. Nevertheless, these findings open new perspectives on post-TIA management.

This research highlights the need to consider mini-strokes not only as transient events but also as potential factors for lasting disorders.

What is a mini-stroke?

A mini-stroke, or transient ischemic attack (TIA), is a temporary interruption of blood supply to part of the brain. Unlike a full stroke, TIA symptoms usually disappear within 24 hours.

The causes of a TIA are similar to those of a stroke, including blood clots or fatty deposits in the arteries. Although temporary, TIAs are serious warning signs and require immediate medical attention.

Diagnosing a TIA relies on symptom assessment and brain imaging tests. Despite the brief duration of symptoms, TIAs can leave subtle but significant aftereffects, as shown in this study on persistent fatigue.

Preventing TIAs involves managing cardiovascular risk factors, such as hypertension, diabetes, and smoking. Early intervention can reduce the risk of subsequent strokes.