Atoportuninae Števčić, 2005
- Atoportunus Ng & Takeda, 2003
- Laleonectes Manning & Chace, 1990
- †Euronectes Karasawa, Schweitzer & Feldmann, 2008
Caphyrinae Paulson, 1875
- Caphyra Guérin, 1832
- Coelocarcinus Edmondson, 1930
- Lissocarcinus Adams & White, 1849
- †Mioxaiva Müller, 1978
Carupinae Paulson, 1875
- Carupa Dana, 1851
- Richerellus Manning & Felder, 1989
- †Neptocarcinus Lőrenthey, 1898
- †Rakosia Müller, 1984
Lupocyclinae Paulson, 1875
- Carupella Lenz, in Lenz & Strunck, 1914
- Lupocyclus Adams & White, 1849
Necronectinae Glaessner, 1928
- †Necronectes A. Milne-Edwards, 1881
- Sanquerus Manning, 1989
- Scylla De Haan, 1833
Podophthalminae Dana, 1851
- Euphylax Stimpson, 1860
- Podophthalmus Lamarck, 1801
- †Psygmophthalmus Schweitzer, Iturralde-Vinent, Hetler & Velez-Juarbe, 2006
- †Sandomingia Rathbun, 1919
- †Saratunus Collins, Lee & Noad, 2003
- †Viaophthalmus Karasawa, Schweitzer & Feldmann, 2008
Portuninae Rafinesque, 1815
- Arenaeus Dana, 1851
- Callinectes Stimpson, 1860
- Cronius Stimpson, 1860
- Lupella Rathbun, 1897
- Portunus Weber, 1795
- †Acanthoportunus Schweitzer & Feldmann, 2002
- †Colneptunus Lőrenthey, in Lőrenthey & Beurlen, 1929
- †Pseudoachelous Portell & Collins, 2004
- †Rathbunella Collins, in Collins, Portell & Donovan, 2009
Thalamitinae Paulson, 1875
- Charybdis De Haan, 1833
- Gonioinfradens Leene, 1938
- Thalamita Latreille, 1829
- Thalamitoides A. Milne-Edwards, 1869
- †Eocharybdis Beschin, Busulini, De Angeli & Tessier, 2002
Sous-famille indéterminée
- †Enoplonotus A. Milne-Edwards, 1860
